Lv72
4785 积分 2020-04-09 加入
Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain
14天前
已完结
Structural basis for selective and potent degradation of IRAK4 by KT-474
20天前
已完结
On the relationship between hERG inhibition and the magnitude of QTc prolongation: An in vitro to clinical translational analysis
25天前
已完结
Misconceptions among medicinal chemists regarding ADME and PK optimization
25天前
已完结
Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design
26天前
已完结
Characteristics of anticancer activity of CBP/p300 inhibitors – Features of their classes, intracellular targets and future perspectives of their application in cancer treatment
27天前
已完结
Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
27天前
已完结
Design, Synthesis, and Characterization of a Series of Cytochrome P4503A-Activated Prodrugs (HepDirect Prodrugs) Useful for Targeting Phosph(on)ate-Based Drugs to the Liver§
27天前
已完结
Discovery of pyrazole-based selective covalent ITK inhibitors with In vivo activity
29天前
已完结
Structure-Guided Discovery of Novel Dual-Site FEM1B Ligands and Assessment of Their Use in Targeted Protein Degradation
29天前
已完结
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