Lv74
4805 积分 2020-04-09 加入
Development of covalent inhibitors: Principle, design, and application in cancer
9天前
已完结
Structural and functional insights into PPAR-γ: Review of its potential and drug design innovations for the development of antidiabetic agents
16天前
已完结
First-of-Its-Kind PPARG Inhibitor Shows Compelling Activity
16天前
已关闭
Inverse Agonists of Peroxisome Proliferator-Activated Receptor Gamma: Advances and Prospects in Cancer Treatment
16天前
已完结
Structure–Activity Relationship Studies toward the Optimization of First-In-Class Selective Small Molecule Agonists of the GPCR Relaxin/Insulin-like Family Peptide Receptor 2
16天前
已完结
Optimization of Covalent Warhead Trajectory for KRAS G12C Active-State Inhibition
16天前
已完结
Optimization of α-Fluoro, β-Heteroaryl Acrylamide Warheads for KRAS G12C Active-State Inhibition
16天前
已完结
A Type-II Kinase Inhibitor Capable of Inhibiting the T315I “Gatekeeper” Mutant of Bcr-Abl
17天前
已完结
Discovery of Gut-Restricted Small-Molecule Inhibitors of Intestinal Sodium-Dependent Phosphate Transport Protein 2b (NaPi2b) for the Treatment of Hyperphosphatemia
19天前
已完结
Discovery of Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1)
19天前
已完结