Lv7
4785 积分 2020-04-09 加入
A DRUG HUNTER’S APPROACH TO MOLECULAR GLUES
3天前
已完结
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
6天前
已完结
TREM2 activation by first-in-class direct small molecule agonists: DEL screening, optimization, biophysical validation, and functional characterization
6天前
已完结
Quinoline-Pyrazole Scaffold as a Novel Ligand of Galectin-3 and Suppressor of TREM2 Signaling
6天前
已完结
Targeting Gatekeeper Mutations for Kinase Drug Discovery
9天前
已完结
Targeting Gatekeeper Mutations for Kinase Drug Discovery
11天前
已完结
Medicinal Chemistry Strategies for the Development of Kinase Inhibitors Targeting Point Mutations
11天前
已完结
Medicinal Chemistry Strategies for the Development of Bruton’s Tyrosine Kinase Inhibitors against Resistance
11天前
已完结
Structure-Function Relationships of Covalent and Non-Covalent BTK Inhibitors
11天前
已完结
Acrylamide Bioisosterism: Alkenyl Aromatic Heterocycles as Reactivity-Tunable Warheads for Covalent BTK Inhibitors
11天前
已完结
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