Lv4
580 积分 2024-05-01 加入
Recent advances in the development of RIPK2 modulators for the treatment of inflammatory diseases
6天前
已完结
Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases
6天前
已完结
Design, synthesis, and structure-activity relationship of novel RIPK2 inhibitors
6天前
已完结
Optimization of a Series of RIPK2 PROTACs
6天前
已完结
Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases
6天前
已完结
The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease
6天前
已完结
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK 2 in NOD 2 signaling
6天前
已完结
A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression
1个月前
已完结
Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9
1个月前
已完结
MLLT1/3 targeted protein degradation as the best-in-class approach for targeting the super elongation complex (SEC) in acute leukemia, including menin inhibitor refractory disease
1个月前
已完结
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