Lv31
294 积分 2022-08-29 加入
Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery
3小时前
待确认
Discovery of Zilucoplan: A Complement C5 Inhibitor for Treatment of Anti-Acetylcholine Receptor (AChR) Antibody-Positive Generalized Myasthenia Gravis (gMG)
13天前
已完结
Derisking Affinity Optimization for Macrocycles and Cyclic Peptides: High-Precision Free Energy Simulations across Five Diverse Targets
22天前
已完结
Selective Targeting of STAT6: Recent Advances and Future Perspectives
22天前
已完结
EnsembleCycPerm: Interpretable Modeling of Cyclic Peptide Permeability through Solvent-Dependent Conformational Ensembles
23天前
已完结
Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d
27天前
已完结
Structural insights into small-molecule KRAS inhibitors for targeting KRAS mutant cancers
28天前
已完结
Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7
1个月前
已完结
Generative molecular design in low data regimes
4个月前
已完结
PropMolFlow: Property-guided Molecule Generation with Geometry-Complete Flow Matching
4个月前
已完结
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