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50 积分 2022-03-07 加入
Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
4小时前
待确认
Structures and mechanism of human mitochondrial pyruvate carrier
5天前
已完结
Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer
17天前
已完结
Novel Sulfonylurea-Based NLRP3 Inflammasome Inhibitor for Efficient Treatment of Nonalcoholic Steatohepatitis, Endotoxic Shock, and Colitis
17天前
已完结
A Pan-KRAS Inhibitor Impedes Common KRAS Oncoproteins and Tumor Growth
17天前
已完结
Site-specific mutagenesis screening in KRAS mutant library to uncover resistance mechanisms to KRASG12D inhibitors
17天前
已完结
Discovery of BI-2493, a Pan-KRAS Inhibitor Showing In Vivo Efficacy
17天前
已完结
Identification of Novel pan-KRAS Inhibitors via Structure-Based Drug Design, Scaffold Hopping, and Biological Evaluation
17天前
已完结
Targeting Nav1.8 with the nonopioid antagonist suzetrigine in analgesia: cause for optimism?
23天前
已完结
Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: A systematic review and meta-analysis
1个月前
已完结
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