Lv4
490 积分 2022-03-07 加入
Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo Activity
6天前
已完结
Characterization of BHV-7000: A Novel Kv7.2/7.3 Activator for the Treatment of Seizures (S29.006)
14天前
已完结
Exploring the GDP binding to KRas WT, G12C, G12D, G12R, and G12V and bound with MRTX1133 using steered molecular dynamics
30天前
已完结
Targeting methionine-induced pyroptosis enhances anti-tumor immunity
30天前
已完结
Discovery of Novel 2,3-Dihydro-1H-indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis
2个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
3个月前
已完结
Type 2 chronic inflammatory diseases: targets, therapies and unmet needs
4个月前
已完结
Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
4个月前
已完结
Structures and mechanism of human mitochondrial pyruvate carrier
5个月前
已完结
Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer
5个月前
已完结
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