Lv11
30 积分 2022-03-07 加入
Discovery of Novel 2,3-Dihydro-1H-indene-5-sulfonamide NLRP3 Inflammasome Inhibitors Targeting Colon as a Potential Therapy for Colitis
1小时前
待确认
Lessons learned in linking PROTACs from discovery to the clinic
30天前
已完结
Type 2 chronic inflammatory diseases: targets, therapies and unmet needs
2个月前
已完结
Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
2个月前
已完结
Structures and mechanism of human mitochondrial pyruvate carrier
2个月前
已完结
Design, synthesis and biological evaluation of pyrrolopyrimidine urea derivatives as novel KRASG12C inhibitors for the treatment of cancer
3个月前
已完结
Novel Sulfonylurea-Based NLRP3 Inflammasome Inhibitor for Efficient Treatment of Nonalcoholic Steatohepatitis, Endotoxic Shock, and Colitis
3个月前
已完结
A Pan-KRAS Inhibitor Impedes Common KRAS Oncoproteins and Tumor Growth
3个月前
已完结
Site-specific mutagenesis screening in KRAS mutant library to uncover resistance mechanisms to KRASG12D inhibitors
3个月前
已完结
Discovery of BI-2493, a Pan-KRAS Inhibitor Showing In Vivo Efficacy
3个月前
已完结
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