Lv1
44 积分 2026-03-06 加入
High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration
24天前
已完结
Dihydroartemisinin inhibits histone lactylation through YAP1 to act as a ‘hot’ switch for ‘cold’ tumor in hepatocellular carcinoma
24天前
已完结
Tumor-associated Schwann cell remodeling under metabolic stress via lactate sensing orchestrates pancreatic ductal adenocarcinoma development
24天前
已完结
Histone H4K8 lactylation modulated immunosuppressive properties by promoting FAP transcription and ECM remodeling
24天前
已完结
Targeting lactylation reinforces NK cell cytotoxicity within the tumor microenvironment
24天前
已完结
Endoplasmic reticulum stress-induced histone lactylation mediating immune escape of gastric cancer via PDIA6 overexpression in dendritic cells
24天前
已完结
High throughput screening identifies sanguinarine chloride as a multi-faceted therapeutic agent for PRCC-TFE3 rRCC by targeting lactylation-driven VEGFB-VEGFR2 signaling and PMN-MDSC infiltration
24天前
已关闭
ICAT drives lactylation of tumor-associated macrophages via the c-Myc-ENO1 axis to promote cervical cancer progression
24天前
已完结
Histone lactylation bridges metabolic reprogramming with chromatin-immune crosstalk in triple-negative breast cancer
24天前
已完结
EVA1A facilitates glycolysis in esophageal squamous cell carcinoma to boost PLAU histone lactylation and dampen CD8+ T cell activity
24天前
已完结
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