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382 积分 2025-11-14 加入
Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders
22小时前
已完结
Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer
22小时前
已完结
Discovery of potential novel CRBN modulators by virtual screening and bioassay
1天前
已完结
Identification of novel GSPT1 degraders by virtual screening and bioassay
1天前
已完结
Discovery of potential novel CRBN modulators by virtual screening and bioassay
1天前
已完结
Development and therapeutic potential of GSPT1 molecular glue degraders: A medicinal chemistry perspective
1天前
已完结
The novel protein homeostatic modulator BTX306 is active in myeloma and overcomes bortezomib and lenalidomide resistance
1天前
已完结
Geometric Interaction Graph Neural Network for Predicting Protein–Ligand Binding Affinities from 3D Structures (GIGN)
15天前
已完结
Discovery of potential novel CRBN modulators by virtual screening and bioassay
1个月前
已完结
SJPYT-195: A Designed Nuclear Receptor Degrader That Functions as a Molecular Glue Degrader of GSPT1
1个月前
已完结
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