Lv3
310 积分 2025-11-14 加入
Targeting Bromodomain and Extraterminal Proteins for Drug Discovery: From Current Progress to Technological Development
12天前
已完结
Dual‐target inhibitors of bromodomain and extra‐terminal proteins in cancer: A review from medicinal chemistry perspectives
12天前
已完结
Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer
12天前
已完结
Discovery of a Highly Potent and Orally Bioavailable STAT3 Dual Phosphorylation Inhibitor for Pancreatic Cancer Treatment
23天前
已完结
Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma
1个月前
已完结
The therapeutic antibody sacituzumab induces trophoblast cell-surface antigen-2 conformational rearrangement
4个月前
已完结
Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders
7个月前
已完结
Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer
7个月前
已完结
Discovery of potential novel CRBN modulators by virtual screening and bioassay
7个月前
已完结
Identification of novel GSPT1 degraders by virtual screening and bioassay
7个月前
已完结
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