Lv2
130 积分 2023-12-06 加入
Design, Synthesis, and Biological Evaluation of Androgen Receptor (AR) Antagonist-Heat Shock Protein 90 (Hsp90) Inhibitor Conjugates for Targeted Therapy of Castration-Resistant Prostate Cancer
1个月前
已完结
Discovery of CBPD-409 as a Highly Potent, Selective, and Orally Efficacious CBP/p300 PROTAC Degrader for the Treatment of Advanced Prostate Cancer
1个月前
已完结
Lisaftoclax (APG-2575) Is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy
3个月前
已完结
Understanding the Functional Dependence and Inhibition of the Bcl-2 Pro-Survival Proteins in a Wide Spectrum of Cancers toward Precision Medicine
4个月前
已完结
Rapid, Operationally Simple, and Metal‐free NBS Mediated One‐pot Synthesis of 1,2‐Naphthoquinone from 2‐Naphthol
5个月前
已完结
Optimization of BAX trigger site activator BTSA1 with improved antitumor potency and in vitro ADMET properties
6个月前
已完结
Drug-Drug Interactions and Synergy: From Pharmacological Models to Clinical Application
6个月前
已完结
Inhibition of oligomeric BAX by an anti-apoptotic dimer
8个月前
已完结
Mechanistic Physiologically Based Pharmacokinetic Modeling of the Dissolution and Food Effect of a Biopharmaceutics Classification System IV Compound—The Venetoclax Story
8个月前
已完结
β-Lactamase Inhibitors Derived from Single-Domain Antibody Fragments Elicited in the Camelidae
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