Lv1
20 积分 2025-02-20 加入
Proximity-inducing modalities: the past, present, and future
17天前
已完结
Research Progress in Targeting GSPT1: Molecular Glues, Bifunctional Degraders, and Antibody-Enabled Molecular Glues for Cancer Therapy
17天前
已完结
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity
22天前
已完结
The cellular thermal shift assay for evaluating drug target interactions in cells
22天前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
2个月前
已完结
Induced proximity pushes beyond protein degraders, as first RIPTAC moves into the clinic
2个月前
已完结
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies
2个月前
已完结
Discovery, Optimization, and Preclinical Pharmacology of EP652, a METTL3 Inhibitor with Efficacy in Liquid and Solid Tumor Models
3个月前
已完结
Discovery, Optimization, and Preclinical Pharmacology of EP652, a METTL3 Inhibitor with Efficacy in Liquid and Solid Tumor Models
3个月前
已完结
HDAC1/3-Dependent Moderate Liquid-Liquid Phase Separation of YY1 Promotes METTL3 Expression and AML Cell Proliferation
3个月前
已关闭
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