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504 积分 2024-09-26 加入
ZE74-0282 is a novel JH2 domain JAK2 inhibitor with promising pre-clinical activity in JAK2 V617F mutant diseases
5小时前
求助中
Discovery of JAK2V617F mutant specific allosteric inhibitors for the treatment of myeloproliferative neoplasms
6小时前
求助中
Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055
12天前
已完结
Structure and Inhibitor Binding Characterization of Oncogenic MLLT1 Mutants
12天前
已完结
Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
16天前
已完结
Overexpression of Cdk6–cyclin D3 highly sensitizes cells to physical and chemical transformation
17天前
已完结
CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
1个月前
已完结
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306
2个月前
已完结
Insight into the mechanism of allosteric activation of PI3Kα by oncoprotein K-Ras4B
2个月前
已完结
Fluorescence Enhancement of 7-Diethylamino-4-methylcoumarin by Noncovalent Dipolar Interactions with Cucurbiturils
3个月前
已完结
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