Lv11
80 积分 2022-01-22 加入
Structure-Guided Discovery of Potent, Selective, and Orally Bioavailable Werner Syndrome RecQ Helicase Inhibitors for the Treatment of Microsatellite Instability-High Tumors
4小时前
已完结
Discovery of Casdatifan, Part II: A Potent and Orally Bioavailable Inhibitor of Hypoxia Inducible Factor-2α
4小时前
已完结
Discovery of CNS Penetrant SOS1 Inhibitors for the Treatment of KRAS-Dependent Cancers
5小时前
已完结
Discovery of Small Molecule Ligands Targeting Orphan G Protein-Coupled Receptors GPR3, GPR6, and GPR12
5小时前
已完结
Discovery of an Orally Available Potent ER Aminopeptidase 1 (ERAP1) Inhibitor That Enhances Antitumor Responses and Limits Inflammatory Autoimmunity In Vivo
5小时前
已完结
Selective CDK2 Degradation via Noncanonical Recruitment
5小时前
已完结
A first-in-class pulsatile FXR agonist for bile-acid-related liver diseases
13天前
已完结
Pharmacological Targeting of IRF4 As a Therapeutic Strategy for Multiple Myeloma
14天前
已完结
星状神经节阻滞疗法中国专家共识(2022版)
15天前
已完结
Multivalent linkers: A growing trend in antibody–drug conjugate development
20天前
已完结