Lv22
160 积分 2022-01-22 加入
Biologic degraders push forward in the clinic
2小时前
已完结
Dually Acting Ligands Targeting Serotonin Receptors: Implications in CNS Disorders
7天前
已完结
Discovery of Casdatifan, Part I: Design and Characterization of Tetrahydroquinoline Inhibitors of Hypoxia-Inducible Factor-2α
7天前
已完结
Discovery of Potent and Selective Benzothiophene Difluoromethyl Phosphonate (DFMP) PTPN2/N1-Dual Inhibitors
7天前
已完结
Design and Synthesis of USP1 Inhibitors: Synergistic Antitumor Activity with PARP Inhibitors in Triple-Negative Breast Cancer
7天前
已完结
Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent Binders
7天前
已完结
DMPK Considerations for the Development of Covalent Drugs: Insights from an IQ Assessment
7天前
已完结
Discovery of Benzofuran-2-Carboxylic Acid Derivatives as Potent PTPRO Inhibitors with Oral Efficacy for Treatment of Inflammatory Bowel Disease
7天前
已完结
New Reversible Covalent Warheads: Cyanobenzothiazoles Recruiting DCAF16 for Targeted Protein Degradation
7天前
已完结
Design and Discovery of Pyridazinone-Based MAT2A Inhibitors Targeting MTAP-Deficient Cancers
7天前
已完结