Lv21
118 积分 2022-01-22 加入
The design and synthesis of selective and potent selenium-containing KRASG12D inhibitors
2天前
已完结
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin
4天前
已完结
A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
6天前
已完结
Chemical Proteomics Identifies RBBP7 as a New E3 Ligase Supporting Targeted Protein Degradation
9天前
已完结
Multigram-Scale Synthesis and Study of Reactivity of Two Difluoromethylating Reagents Based on Sulfoximine Skeletons
9天前
已完结
Discovery of KBD4466, a Selective TLR 7/8 Inhibitor, for the Treatment of Autoimmune Diseases
12天前
已完结
Peptidylarginine Deiminase (PAD) Inhibitor Optimization through Displacement of a Trapped Water Molecule
15天前
已完结
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists
17天前
已完结
Discovery of Thiochroman Derivatives as Potent, Oral Selective Estrogen Receptor Degraders and Antagonists for the Treatment of Endocrine-Resistant Breast Cancer
17天前
已完结
Discovery of an Orally Bioavailable and Brain Penetrant Selective Estrogen Receptor Degrader
17天前
已完结
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