Lv5
1250 积分 2022-03-21 加入
Deciphering SHP-2 conformational switching via elastic network models and transfer entropy analysis
4小时前
待确认
Universal pipeline for high-resolution GPCR structure determination
15天前
已完结
Comparative binding mechanisms of SND1 with MTDH and small-molecule inhibitors: insights from molecular dynamics simulations and free energy calculations
1个月前
已完结
AlloPath: A method for identifying protein allosteric pathway based on transfer entropy and hidden Markov model
2个月前
已完结
Decoding the selective mechanism behind a monobody inhibitor to the phosphatase domain of SHP2: insights from molecular dynamics simulations
2个月前
已完结
Unveiling the molecular mechanism of Gi protein biased activation at mGlu2–mGlu4 heterodimers through Gaussian accelerated molecular dynamics simulations
5个月前
已完结
Development of a clinically viable MRGPRX4 inverse agonist for cholestatic itch treatment
5个月前
已完结
gmx_RRCS: A Precision Tool for Detecting Subtle Conformational Dynamics in Molecular Simulations
5个月前
已完结
Mechanistic Insights into the Long-range Allosteric Regulation of KRAS Via Neurofibromatosis Type 1 (NF1) Scaffold Upon SPRED1 Loading
5个月前
已完结
Integrative computational simulations and functional assays decode allosteric dysregulation in a pathogenic SIRT6 variant
5个月前
已完结
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