Lv6
1720 积分 2025-02-13 加入
A New Synthesis of Gefitinib
14天前
已完结
JIN-A02, a Mutant-Selective Fourth-Generation EGFR inhibitor, Overcomes C797S-Mediated Resistance and Demonstrates Intracranial Activity in NSCLC
1个月前
已完结
Targeted degradation of EGFR 19Del by PROTACs suppresses tumor growth in non-small-cell lung cancer
1个月前
已完结
AZ14289671 is a highly selective and blood-brain barrier penetrant irreversible TKI that targets EGFRExon20 insertions
1个月前
已完结
Covalent Alkynylpyridopyrimidinones Targeting Cysteine 775 of the Epidermal Growth Factor Receptor Overcome Resistance to Current Therapies
1个月前
已完结
Discovery of Potent and Selective Pyrrolo[2,3-d]pyrimidine Derivatives as Fourth-Generation EGFR Inhibitors Targeting Triple Mutations
1个月前
已完结
Discovery of new cyclopropane sulfonamide derivatives as EGFR inhibitors to overcome C797S-mediated resistance and EGFR double mutation
1个月前
已完结
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations
1个月前
已完结
Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19
1个月前
已完结
Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448)
1个月前
已完结
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