Lv511
840 积分 2025-12-22 加入
Efficacy studies of an antibody‐drug conjugate PSMA‐ADC in patient‐derived prostate cancer xenografts
1天前
已完结
Concentration–QTc analysis for single arm studies
1个月前
已完结
Practical guide to concentration-QTc modeling: a hands-on tutorial
1个月前
已完结
Assessing QT/QTc interval prolongation with concentration-QT modeling for Phase I studies: impact of computational platforms, model structures and confidence interval calculation methods
1个月前
已完结
Sample size determination for cardiodynamic ECG assessment using the Concentration-QTc analysis method
1个月前
已完结
Preclinical Pharmacokinetics of MI-219, a Novel Human Double Minute 2 (HDM2) Inhibitor and Prediction of Human Pharmacokinetics
1个月前
已完结
Quantitative prediction of human pharmacokinetics and pharmacodynamics of imigliptin, a novel DPP-4 inhibitor, using allometric scaling, IVIVE and PK/PD modeling methods
1个月前
已完结
Translational prediction of first-in-human pharmacokinetics and pharmacodynamics of janagliflozin, a selective SGLT2 inhibitor, using allometric scaling, dedrick and PK/PD modeling methods
1个月前
已完结
Preclinical assessment of the PI3Kα selective inhibitor inavolisib and prediction of its pharmacokinetics and efficacious dose in human
2个月前
已完结
Dose translation between laboratory animals and human in preclinical and clinical phases of drug development
2个月前
已完结
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