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450 积分 2025-12-22 加入
Practical guide to concentration-QTc modeling: a hands-on tutorial
23小时前
待确认
Assessing QT/QTc interval prolongation with concentration-QT modeling for Phase I studies: impact of computational platforms, model structures and confidence interval calculation methods
1天前
已完结
Sample size determination for cardiodynamic ECG assessment using the Concentration-QTc analysis method
2天前
已完结
Preclinical Pharmacokinetics of MI-219, a Novel Human Double Minute 2 (HDM2) Inhibitor and Prediction of Human Pharmacokinetics
6天前
已完结
Quantitative prediction of human pharmacokinetics and pharmacodynamics of imigliptin, a novel DPP-4 inhibitor, using allometric scaling, IVIVE and PK/PD modeling methods
6天前
已完结
Translational prediction of first-in-human pharmacokinetics and pharmacodynamics of janagliflozin, a selective SGLT2 inhibitor, using allometric scaling, dedrick and PK/PD modeling methods
6天前
已完结
Preclinical assessment of the PI3Kα selective inhibitor inavolisib and prediction of its pharmacokinetics and efficacious dose in human
16天前
已完结
Dose translation between laboratory animals and human in preclinical and clinical phases of drug development
16天前
已完结
Scientific white paper on concentration-QTc modeling
17天前
已完结
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Stapokibart in Healthy Volunteers and Adult Subjects with Atopic Dermatitis
19天前
已完结
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