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110 积分 2025-08-08 加入
Discovery of novel and potent NLRP3 inflammasome inhibitors with new lipophilic moieties
6天前
已完结
Inhibition of NLRP3 Signalling Improves Kidney Function in Preclinical Models of AKI
6天前
已完结
Rational design of an NLRP3 inhibitor with superior efficacy and safety for gout therapy
6天前
已完结
IL-2Rα-biased agonist enhances antitumor immunity by invigorating tumor-infiltrating CD25+CD8+ T cells
9天前
已完结
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
26天前
已完结
Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis
27天前
已完结
Crystal structure of the IL-15–IL-15Rα complex, a cytokine-receptor unit presented in trans
1个月前
已完结
Abstract 4068: In vitro masked effect, in vivo anti-tumor activity and toxicology study of KGX101, an interleukin-12 prodrug, in monotherapy or in combination with anti-PD-L1 antibody
1个月前
已完结
Macrophage SBK2 suppresses inflammation and atherosclerosis by NLRP3 phosphorylation
2个月前
已完结
An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity
2个月前
已完结
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