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2025 Medicinal Chemistry Reviews
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Major Progress in the Liquid-Phase Synthesis of N -Alkyl-Rich Cyclic Peptides: Kilogram-Scale GMP Production of the KRAS Inhibitor LUNA18
14天前
已完结
A Sustainable Approach to ε-Lys Branched GLP-1 Analogs: Integrating Green SPPS, Metal-free Alloc Removal, Waste Minimization and TFA/PFAS-free Resin Cleavage
14天前
已完结
Route Development toward a Pyrazine Building Block to Enable Early Scale-Up Campaigns
14天前
已完结
Process Development of the Novel LpxC Inhibitor T-1228: Part 3: Optimization of the Deprotection Reaction and the Crystallization for the Final Step of API Synthesis
14天前
已完结
Development of an Optimized Synthetic Process for Onradivir Featuring a “One-Pot” Miyaura–Suzuki Coupling Reaction
14天前
已完结
Process Development of the Novel LpxC Inhibitor T-1228. Part 1: Synthesis of the Diol Fragment
14天前
已完结
Advancing Peptide Synthesis: Liquid-Phase Assembly of Tirzepatide’s C-Terminus (30–39) via Crystalline Pentamer Building Blocks
14天前
已完结
Evolution of the Synthesis Route for CC-99677: From Discovery toward Commercialization
14天前
已完结
Development of a Manufacturing Route toward AMG 193, an MTA-Cooperative PRMT5 Inhibitor
17天前
已完结
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