Lv41
628 积分 2024-01-04 加入
Application of a translational research platform to unveil efficacy signals and mechanisms of resistance of FGFR inhibitors in multiple FGFR -altered solid tumors
1小时前
求助中
Novel Treatment Options for Multiple Myeloma
6天前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
7天前
已完结
The role of E3 ubiquitin ligase in multiple myeloma: potential for cereblon E3 ligase modulators in the treatment of relapsed/refractory disease
7天前
已完结
Abstract B047: dCBP-30: A rationally designed, orally bioavailable, near-linkerless PROTAC for potent CBP/p300 degradation
7天前
已完结
LY3410738, a Covalent Inhibitor of Mutant IDH1/2, is Effective in Acute Myeloid Leukemia Preclinical Models
7天前
已完结
Targeting the Menin– KMT2A Interface: Medicinal Chemistry Rules Governing Reversible, Covalent, and Degrader Inhibitors
10天前
已完结
Menin Inhibitor Induced Menin Protein Degradation Contributes to Menin Inhibitor Efficacy
10天前
已完结
Hope and Hurdles for Menin Inhibitors in Leukemia
10天前
已关闭
Late-stage functionalization with strain-release warheads enables tunable covalent inhibition
10天前
已完结