Lv1
6 积分 2024-05-25 加入
Balancing stability and activation: A pseudoparabolic activity spectrum guides fatty acid chain length optimization in prodrug-albumin nanoparticles
6小时前
已完结
Dual-payload small-molecule drug conjugates enable bystander anticancer activity with reduced nonspecific release
6小时前
已完结
HRA00129-C004, a Novel c-Met Antibody–Drug Conjugate, Exerts Encouraging Antitumor Activities and Favorable Safety Profiles
6小时前
已完结
Stereochemistry of Benzylic Carbon Substitution Coupled with Ring Modification of 2‐Nitrobenzyl Groups as Key Determinants for Fast‐Cleaving Reversible Terminators
5天前
已完结
Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants
12天前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
19天前
已完结
Journey of PROTAC: From Bench to Clinical Trial and Beyond
19天前
已完结
Balancing stability and activation: A pseudoparabolic activity spectrum guides fatty acid chain length optimization in prodrug-albumin nanoparticles
20天前
已完结
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors
20天前
已完结
Preclinical Antitumor Efficacy of a Novel Anti–c-Kit Antibody–Drug Conjugate, NN3201, in c-Kit–Positive Tumors
21天前
已完结
皖公网安备34019202002308
