Lv11
56 积分 2024-05-25 加入
Hydrophobic tag-based protein degradation: Development, opportunity and challenge
9天前
已完结
Two-Step Construction of Thiophene–Oxazole Dyads with Fluorescent Properties by the Ring Expansion of Aziridines
9天前
已关闭
The role of hydrophilic linkers in next-generation antibody-drug conjugates
9天前
已完结
Challenges and approaches to the design of hydrophilic linkers for antibody-drug conjugates
9天前
已完结
Cyclopropenimine-Catalyzed Enantioselective Mannich Reactions of tert -Butyl Glycinates with N -Boc-Imines
13天前
已完结
Direct Asymmetric Reductive Amination of Alkyl (Hetero)Aryl Ketones by an Engineered Amine Dehydrogenase
17天前
已完结
Preclinical characterization of TOS-358, a potent and selective covalent inhibitor of wild-type and mutant PI3Kα with superior anticancer activity
20天前
已完结
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors
27天前
已完结
Discovery of INCB123667, a potent and selective cyclin-dependent kinase 2 (CDK2) inhibitor for the treatment of cyclin E dysregulated cancers
29天前
已完结
DMPK Considerations for the Development of Covalent Drugs: Insights from an IQ Assessment
1个月前
已完结
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