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8 积分 2025-06-03 加入
Toward the Establishment of a Harmonized Physicochemical Profiling Platform for Therapeutic Oligonucleotides: A Case Study for Aptamers Where the Higher-Order Structure Influences Physical Properties
3个月前
已完结
Separation of phosphorothioate oligonucleotide impurities by WAX HPLC under high organic content elution conditions
3个月前
已完结
Assay, Purity, and Impurity Profile of Phosphorothioate Oligonucleotide Therapeutics by Ion Pair–HPLC–MS
3个月前
已完结
A Phase-Appropriate Risk Assessment Strategy in Support of the Safety of Peptide and Oligonucleotide-Related Impurities
3个月前
已完结
Folding Topology of a Short Coiled‐Coil Peptide Structure Templated by an Oligonucleotide Triplex
3个月前
已完结
Bioanalytical approaches to support the development of antibody-oligonucleotide conjugate (AOC) therapeutic proteins
3个月前
已完结
A hydrolyzed N ‐propionylthiosuccinimide linker is cleaved by metastable fragmentation, increasing reliability of conjugation site identification in conjugate vaccines
3个月前
已完结
Label-free, highly sensitive and accurate discrimination of multiple vesicant mustard-DNA adducts using capillary-driven SERS coupled with RP-TLC and algorithm analysis
6个月前
已完结
Independent gradient model based on Hirshfeld partition: A new method for visual study of interactions in chemical systems
8个月前
已完结
Single‐Cell Secretome Profiling Enabled by Selective Enrichment and NanoLC‐MS/MS Analysis
9个月前
已完结