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112 积分 2025-04-02 加入
Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant Cancers
38分钟前
已完结
Rethinking log P : Lipophilicity = Hydrophobicity
1天前
已完结
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors
13天前
已完结
Exploiting Bridged Conformations for Precise Molecular Recognition in the Design of KRAS-Selective, Orally Available Macrocyclic Peptides
1个月前
已完结
Synthetic Approaches to the New Drugs Approved During 2024
4个月前
已完结
Discovery Process of Enlicitide, a Highly Engineered Macrocyclic Peptide Therapeutic, through Issue-Driven Fragment-Based Synthetic Assembly and SAR
5个月前
已完结
Disrupted molecular glue complex drives RAS inhibitor resistance
5个月前
已完结
PROTACs: past, present and future
5个月前
已完结
Chemistries of bifunctional PROTAC degraders
5个月前
已完结
Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitide
5个月前
已完结