Lv11
40 积分 2025-01-14 加入
Unveiling New Binding Sites and Allosteric Regulation Mechanisms of LSD1 for Novel Therapeutics
6小时前
已完结
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
1个月前
已完结
Structure and Mechanism of Lysine-specific Demethylase Enzymes
1个月前
已完结
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure–Activity Relationship
1个月前
已完结
Lysine-Specific Histone Demethylase 1 Promotes Oncogenesis of the Esophageal Squamous Cell Carcinoma by Upregulating DUSP4
2个月前
已完结
LSD1 inhibitors for anticancer therapy: a patent review (2017-present)
2个月前
已完结
Design, synthesis, and biological evaluation of 5‐aminotetrahydroquinoline‐based LSD1 inhibitors acting on Asp375
2个月前
已完结
Development and Structural Evaluation of N‐Alkylated trans‐2‐Phenylcyclopropylamine‐Based LSD1 Inhibitors
3个月前
已完结
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure–Activity Relationship
3个月前
已完结
Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models
3个月前
已完结
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