Lv4
448 积分 2024-12-30 加入
Discovery of WWZ-11-098: a rigid and selective CDK6 degrader
18天前
已完结
Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)
18天前
已完结
Medicinal chemistry perspective on cGAS-STING signaling pathway with small molecule inhibitors
25天前
已完结
Design, synthesis and preclinical evaluation of a tumor extracellular nucleotidase CD73 targeted theranostic radiotracer
1个月前
已关闭
Novel Acyl Thiourea-Based Hydrophobic Tagging Degraders Exert Potent Anti-Influenza Activity through Two Distinct Endonuclease Polymerase Acidic-Targeted Degradation Pathways
1个月前
已完结
The novel SIRT2-targeted PROTAC degraders as the efficient agents for the treatment of ovarian cancer
1个月前
已完结
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders
1个月前
已完结
Design and synthesis of proteolysis targeting chimeras (PROTACs) as an EGFR degrader based on CO-1686
1个月前
已完结
Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic
1个月前
已完结
An orally available non-nucleotide STING agonist with antitumor activity
1个月前
已完结
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