Lv41
438 积分 2024-09-29 加入
Neuroproteasomes regulate endogenous tau paired helical filament formation in an APOE genotype- and age-dependent manner
6小时前
已完结
An unexpected molecular explanation for how tau aggregation begins in Alzheimer’s disease
9小时前
求助中
Discovery of an orally bioavailable, CNS active pan-mutant RET kinase heterobifunctional degrader
1个月前
已完结
A critical appraisal of tau‐targeting therapies for primary and secondary tauopathies
1个月前
已完结
Affinity selection mass spectrometry (AS-MS) as a tool to accelerate drug discovery efforts
2个月前
已完结
Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2
2个月前
已完结
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase
3个月前
已完结
Probing the proteome
3个月前
已完结
Engineering Covalent Aptamer Chimeras for Enhanced Autophagic Degradation of Membrane Proteins
4个月前
已完结
Structure of pancreatic hIAPP fibrils derived from patients with type 2 diabetes
4个月前
已完结
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