Lv9
22850 积分 2022-04-22 加入
Discovery of Highly Selective Inhibitors of Microtubule-Associated Serine/Threonine Kinase-like (MASTL)
7小时前
已完结
140 (PB128): ATV-1601 is a Potent and Selective Allosteric Inhibitor of AKT1-E17K and Shows Profound and Durable Regressions in AKT1-E17K-Driven Patient Derived Xenograft Models
3天前
已完结
The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism
3天前
已完结
Insulin–PI3K signalling: an evolutionarily insulated metabolic driver of cancer
3天前
已完结
Role of insulin receptor substance-1 modulating PI3K/Akt insulin signaling pathway in Alzheimer’s disease
3天前
已完结
Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes
4天前
已完结
Enhanced Retention of NTSR1-Targeted Radionuclide Therapeutics via Covalent Inhibitors in Pancreatic, Colorectal, and Prostate Cancer Models
5天前
已完结
Abstract A096: Discovery of a covalent allosteric inhibitor targeting AKT1 E17K for the treatment of solid tumors
6天前
已关闭
Disrupted molecular glue complex drives RAS inhibitor resistance
10天前
已完结
Disruption of the Interaction of RAS with PI 3-Kinase Induces Regression of EGFR-Mutant-Driven Lung Cancer
10天前
已关闭