Lv3
400 积分 2025-07-24 加入
Identification of a p21-activated kinase 1 (PAK1) inhibitor with 10-fold selectivity against PAK2
5小时前
待确认
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors
1个月前
已完结
Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors
3个月前
已完结
Design, synthesis, and biological evaluation of novel 3-oxo-2,3-dihydropyridazine derivatives as interleukin-2-inducible T-cell kinase (ITK) inhibitors
4个月前
已完结
Therapeutic Targeting of Interleukin-2-Inducible T-Cell Kinase (ITK) for Cancer and Immunological Disorders: Potential Next-Generation ITK Inhibitors
4个月前
已完结
Therapeutic Targeting of Interleukin-2-Inducible T-Cell Kinase (ITK) for Cancer and Immunological Disorders: Potential Next-Generation ITK Inhibitors
4个月前
已完结
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)
5个月前
已完结
A Novel Small Molecule ITK Inhibitor Suppresses Th2/Th17 Differentiation and Attenuates Airway Inflammation in a Mouse Model of HDM‐Induced Asthma
5个月前
已完结
Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitors
5个月前
已完结
Structure‐Based Design, Synthesis, and Biological Evaluation of Hsp90β‐Selective Inhibitors
6个月前
已完结