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960 积分 2025-11-05 加入
Xanomeline: A Potent and Selective M1 Muscarinic Agonist in Vitro
8天前
已完结
Shifting the trajectory of therapeutic development for neurological and psychiatric disorders
1个月前
已完结
The Safety and Tolerance of Xanomeline Tartrate, an M1-Specific Cholinergic Agonist, in Patients with Alzheimer’s Disease
1个月前
已完结
The PET tracer [ 11 C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer’s disease
1个月前
已完结
Classics in Chemical Neuroscience: Xanomeline
2个月前
已完结
Synthesis and evaluation of novel 5-HT2A receptor inverse agonist with excellent in vivo antipsychotic efficacy and superior tissue distribution for treatment of Parkinson’s disease psychosis
2个月前
已完结
GLP-1 Medications May Lower Dementia Risk, Research Shows
3个月前
已完结
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M4 Muscarinic Acetylcholine Receptor
3个月前
已完结
Emraclidine, a novel positive allosteric modulator of cholinergic M4 receptors, for the treatment of schizophrenia: a two-part, randomised, double-blind, placebo-controlled, phase 1b trial
4个月前
已完结
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