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78 积分 2023-12-01 加入
Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network
7天前
已完结
A B7H3-targeting antibody–drug conjugate in advanced solid tumors: a phase 1/1b trial
9天前
已完结
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia
15天前
已完结
Recurrent breakpoints in the BRD4 locus reduce toxicity associated with gene amplification
16天前
已完结
Unrealized targets in the discovery of antibiotics for Gram-negative bacterial infections
29天前
已完结
Structure-guided design of partial agonists at an opioid receptor
1个月前
已完结
MTA-Cooperative PRMT5 Inhibitors: Mechanism Switching Through Structure-Based Design
1个月前
已完结
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor
1个月前
已完结
GPCR drug discovery: new agents, targets and indications
1个月前
已完结
Novel Bicyclic Amines as CDK2 Inhibitors for Treating Metastatic Breast Cancer or Metastatic Lung Cancer
2个月前
已完结
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