Lv11
20 积分 2023-11-09 加入
“Angular” Spirocyclic Azetidines: Synthesis, Characterization, and Evaluation in Drug Discovery
3天前
已完结
A Fit-for-Purpose Synthesis of a Chiral Oxa-azaspiro Building Block
3天前
已完结
Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G Polymorphism
3天前
已完结
Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu-opioid receptor splice variants
4天前
已完结
Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists
4天前
已完结
Allosteric Inhibition of PKMYT1 Induces a Unique, Inactive ATP Binding Site Conformation
5天前
已完结
Exploiting the Power of Stereochemistry in Drug Action: 3-[(2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as Potent Sigma-1 Receptor Antagonist
5天前
已完结
Redefining Drug Immune Recognition: A Radically Reconfigured Molecular Architecture Enables Broad Fentanyl-Class Protection
5天前
已完结
From Scaffold Optimization to a Promising Lead: Discovery of a Novel Roemerine Analogue, a Multichannel Antiarrhythmic with Low hERG Liability and Functional Restoration Capacity
7天前
已完结
Ladderanes: Stepping Up as Nonclassical ortho -Substituted Benzene Bioisosteres
7天前
已完结
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