Lv669
1789 积分 2021-07-11 加入
Current developments in PI3K-based anticancer agents: Designing strategies, biological activity, selectivity, structure-activity correlation, and docking insight
3天前
已完结
Pten, PI3K, and PtdIns(3,4,5)P3 dynamics control pulsatile actin branching in Drosophila retina morphogenesis
7天前
已完结
Genomic Alterations in PIK3CA -Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα Inhibitors
8天前
已完结
Physiological expression of PI3K H1047R mutation reveals its anti-metastatic potential in ErbB2-driven breast cancer
8天前
已完结
High throughput application of the NanoBiT Biochemical Assay for the discovery of selective inhibitors of the interaction of PI3K-p110α with KRAS
8天前
已完结
A patent review of mutant-selective PI3Kα inhibitors for the treatment of different cancers (2021–2025)
8天前
已完结
Direct activation of PI3K in osteoblasts and osteocytes strengthens murine bone through sex-specific actions on cortical surfaces
9天前
已完结
Discovery of Novel Disubstituted l -Prolinamide Derivatives as Selective PI3Kα Inhibitors for Anticancer Therapy
9天前
已完结
Angiogenic switching in cerebral cavernous malformations driven by MAP3K3–PIK3CA synergy
9天前
已完结
Rational Design of Potent and Orally Efficacious PI3Kα/δ Degrader for PIK3CA Mutant Breast Cancer without Hyperglycemic Liability
9天前
已完结
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