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46 积分 2024-11-01 加入
Zanzalintinib plus atezolizumab versus regorafenib in refractory colorectal cancer (STELLAR-303): a randomised, open-label, phase 3 trial
1个月前
已完结
JOSD1 drives hepatocellular carcinoma malignancy by modulating the ubiquitination-lactylation switch on PGAM1
1个月前
已完结
JOSD1 drives hepatocellular carcinoma malignancy by modulating the ubiquitination-lactylation switch on PGAM1
1个月前
已完结
KRAS mutation-driven O-GlcNAcylation of CLDN18.2 enhances the progression of pancreatic cancer and reduces the efficacy of CLDN18.2-targeted therapy
1个月前
已完结
Extracellular CD44 lactylation impairs CD8+ T cell function in KRAS-mutant colorectal cancer
4个月前
已完结
GCN5–ERK lactylation–phosphorylation loop amplifies lactate-driven cancer progression
5个月前
已完结
IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma
5个月前
已完结
Inhibiting macrophage-derived lactate transport restores cGAS–STING signalling and enhances antitumour immunity in glioblastoma
5个月前
已完结
Targeting MondoA–TXNIP restores antitumour immunity in lactic-acid-induced immunosuppressive microenvironment
6个月前
已完结
Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth
6个月前
已完结
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