Lv1
38 积分 2025-11-24 加入
Design, synthesis and bioevaluation of PI3Kα-selective inhibitors as potential colorectal cancer drugs
9小时前
已完结
Discovery of an Orally Bioavailable STING Inhibitor with In Vivo Anti-Inflammatory Activity in Mice with STING-Mediated Inflammation
7天前
已完结
Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia
11天前
已完结
Discovery of Novel Isoxazole-Based FXR Agonists Containing a 1,2,4-Oxadiazol-5(4H)-one Ring
11天前
已完结
Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2
11天前
已完结
Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors
15天前
已完结
Progress In the Chemistry and Pharmacology of Isoindolin‐1‐One Scaffolds
15天前
已完结
Structure-Guided Design of a Highly Selective PI3Kα Inhibitor Overcoming Metabolic Dysregulation with Potent Anti-breast Cancer Efficacy
18天前
已完结
Discovery of Novel Disubstituted l -Prolinamide Derivatives as Selective PI3Kα Inhibitors for Anticancer Therapy
18天前
已完结
Identification of 5,7-Dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one Derivatives as ENPP1 Inhibitors for STING Pathway-Mediated Immunotherapy
21天前
已完结
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