Lv2
130 积分 2025-12-16 加入
Stereoselective synthesis of pentasubstituted 1,3-dienes via Ni-catalyzed reductive coupling of unsymmetrical internal alkynes
11分钟前
求助中
Structural basis for dual targeting of μ-opioid and nociceptin/orphanin FQ receptors by Cebranopadol
3小时前
已完结
2-Aryl and 2-Heteroaryl Indoles from 1-Alkynes ando-Iodotrifluoroacetanilide through a Domino Copper-Catalyzed Coupling−Cyclization Process
21天前
已完结
Stepwise and one-pot cross-coupling–heteroannulation approaches toward 2-substituted C5-, C6-, and C7-nitroindoles
27天前
已完结
Discovery of Bis-imidazolecarboxamide Derivatives as Novel, Potent, and Selective TNIK Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
30天前
已完结
Heteroaryl-substituted naphthalenes and structurally modified derivatives: selective inhibitors of CYP11B2 for the treatment of congestive heart failure and myocardial fibrosis
1个月前
已完结
In Vivo Active Aldosterone Synthase Inhibitors with Improved Selectivity: Lead Optimization Providing a Series of Pyridine Substituted 3,4-Dihydro-1H-quinolin-2-one Derivatives
1个月前
已完结
Iridium and B(C6F5)3 co-catalyzed chemoselective deoxygenative reduction of tertiary amides: application to the efficient synthesis and late-stage modification of pharmaceuticals
1个月前
已完结
Simple, versatile, and chemoselective reduction of secondary amides and lactams to amines with the Tf2O–NaBH4 or Cp2ZrHCl–NaBH4 system
1个月前
已完结
Direct, One‐pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents through Lactam/Amide Activation
1个月前
已完结