Lv41
600 积分 2023-01-16 加入
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
3小时前
已完结
Plasticity in binding confers selectivity in ligand-induced protein degradation
4小时前
已完结
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
4个月前
已完结
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin
4个月前
已完结
A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
4个月前
已完结
Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279
4个月前
已完结
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165
4个月前
已完结
Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712
4个月前
已完结
Mapping Water Thermodynamics on Drug Candidates via Molecular Building Blocks: a Strategy to Improve Ligand Design and Rationalize SAR
5个月前
已完结
皖公网安备34019202002308
