Lv4
660 积分 2023-01-16 加入
Structural insight into selectivity of amylin and calcitonin receptor agonists
10小时前
待确认
Discovery and Characterization of PVTX-321 as a Potent and Orally Bioavailable Estrogen Receptor Degrader for ER+/HER2– Breast Cancer
11天前
已完结
Discovery of Atirmociclib (PF-07220060): A Potent and Selective CDK4 Inhibitor
1个月前
已完结
CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
1个月前
已完结
Identification of triazolyl KAT6 inhibitors via a templated fragment approach
2个月前
已完结
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
2个月前
已完结
Plasticity in binding confers selectivity in ligand-induced protein degradation
2个月前
已完结
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
7个月前
已完结
Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin
7个月前
已完结
A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
7个月前
已完结
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