Lv3
244 积分 2025-10-16 加入
X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson’s Disease Mouse Model
1天前
已完结
Prodrugs as Drug Delivery Systems IV: N-mannich bases as Potential Novel Prodrugs for Amides, Ureides, Amines, and Other NH-acidic Compounds
18天前
已完结
Carboxamido Derivatives of the Tetracyclines
18天前
已完结
Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases
18天前
已完结
Design and Characterization of a Pyridone-Containing EZH2 Inhibitor Phosphate Prodrug
18天前
已完结
Hydrolysis of N-Mannich bases and its consequences for the biological testing of such agents
19天前
已完结
Prodrugs as Drug Delivery Systems IV: N-mannich bases as Potential Novel Prodrugs for Amides, Ureides, Amines, and Other NH-acidic Compounds
19天前
已完结
A Practical Synthesis of the Pseudotripeptide RC-1291
20天前
已完结
Discovery of Selective LRRK2 Inhibitors Guided by Computational Analysis and Molecular Modeling
1个月前
已完结
Ser 1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations
1个月前
已完结