Lv3
356 积分 2025-09-19 加入
A highly selective JAK3 inhibitor is developed for treating rheumatoid arthritis by suppressing γc cytokine–related JAK-STAT signal
2个月前
已完结
Discovery of YJZ5118: A Potent and Highly Selective lrreversibleCDK12/13 Inhibitor with Synergistic Effects in Combination with Aktinhibition
3个月前
已完结
Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7
3个月前
已完结
Structure-Based Design and Optimization of Novel, Potent and Selective Covalent FGFR2/3 Inhibitors with a Tricyclic Core
3个月前
已完结
Erdafitinib to treat urothelial carcinoma
5个月前
已完结
Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor
7个月前
已完结
Structure-Based Optimization of the Third Generation Type II Macrocycle TRK Inhibitors with Improved Activity against Solvent-Front, xDFG, and Gatekeeper Mutations
7个月前
已完结
Discovery of Cell-Permeable Macrocyclic Cyclin A/B RxL Inhibitors that Demonstrate Antitumor Activity
7个月前
已完结
具有强效体外和体内抗疟活性的大环模拟肽血浆蛋白酶 X 抑制剂
7个月前
已完结
Discovery of Highly Selective and Potent Macrocyclic JAK2 Inhibitors for the Treatment of MPNs
7个月前
已完结
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