Lv1
10 积分 2025-09-19 加入
Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor
1个月前
已完结
Structure-Based Optimization of the Third Generation Type II Macrocycle TRK Inhibitors with Improved Activity against Solvent-Front, xDFG, and Gatekeeper Mutations
2个月前
已完结
Discovery of Cell-Permeable Macrocyclic Cyclin A/B RxL Inhibitors that Demonstrate Antitumor Activity
2个月前
已完结
具有强效体外和体内抗疟活性的大环模拟肽血浆蛋白酶 X 抑制剂
2个月前
已完结
Discovery of Highly Selective and Potent Macrocyclic JAK2 Inhibitors for the Treatment of MPNs
2个月前
已完结
Secondary Amides of (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase
8个月前
已完结
Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS
8个月前
已完结
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