Lv1
56 积分 2024-11-26 加入
Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
21天前
已完结
TP53 Mutations within T Cells Induce T-Cell Exhaustion and Functional Impairment in TP53 Mutant AML
21天前
已关闭
Targeting TDY induces synthetic lethality and enhances anti-tumor immunity in p53-deficient cancers
23天前
已完结
Discovery of SY-589, a Highly Potent and Orally Bioavailable Polθ Helicase Inhibitor for the Treatment of HR-Deficient Tumors
1个月前
已完结
Targeting thymine DNA glycosylase induces synthetic lethality in p53-deficient cancers
1个月前
已完结
Dynamic regulation of TBK1 lactylation shapes antiviral immune responses
1个月前
已完结
Loss of KDM6A-mediated genomic instability and metabolic reprogramming regulates response to therapeutic perturbations in bladder cancer
1个月前
已完结
NAD+ Sensing by PARP7 Regulates the C/EBPβ-Dependent Transcription Program in Adipose Tissue In Vivo
1个月前
已完结
Stokes AL, et al. (2024). PARP7 is an NAD+ sensor that controls C/EBPβ transcriptional activity and adipogenesis
1个月前
已关闭
Correction: Lactate metabolism in human health and disease
2个月前
已完结