Lv2
120 积分 2025-03-17 加入
Discovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression
14小时前
待确认
Design and Development of IKZF2 and CK1α Dual Degraders
12天前
已完结
CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
16天前
已完结
Discovery of FHD-286, a First-in-Class, Orally Bioavailable, Allosteric Dual Inhibitor of the Brahma Homologue (BRM) and Brahma-Related Gene 1 (BRG1) ATPase Activity for the Treatment of SWItch/Sucrose Non-Fermentable (SWI/SNF) Dependent Cancers
20天前
已完结
Structural analysis of the macrocyclic inhibitor BI-4020 binding to EGFR kinase
1个月前
已完结
Biochemical Profiling and Structural Basis of ADAR1-Mediated RNA Editing
1个月前
已完结
Targeting ADAR1 with a small molecule for the treatment of prostate cancer
1个月前
已完结
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1
1个月前
已完结
Structure of human chromatin-remodelling PBAF complex bound to a nucleosome
1个月前
已完结
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