Lv2
110 积分 2025-12-02 加入
Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors
12小时前
已完结
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)
12小时前
已完结
DNA-Encoded Library (DEL) Selection Identifies a Distinct DDB1 Ligand Binding Site
1个月前
已完结
Advances in the development of hybrid anticancer drugs
1个月前
已完结
Integrated Biochemical and Cellular Validation of SIP0401 as an Isoform-preferential PDE4B Inhibitor
1个月前
已完结
Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors
1个月前
已完结
Design, synthesis and structure–activity relationship of indolylindazoles as potent and selective covalent inhibitors of interleukin-2 inducible T-cell kinase (ITK)
1个月前
已完结
N1-Benzoyl-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes: Development of 4-chlorophenylcarboxamide (calhex 231) as a new calcium sensing receptor ligand demonstrating potent calcilytic activity
1个月前
已完结
Discovery of 7H-pyrrolo[2,3-d]pyrimidine derivatives as selective covalent irreversible inhibitors of interleukin-2-inducible T-cell kinase (Itk)
2个月前
已完结
Selective Itk Inhibitors Block T-Cell Activation and Murine Lung Inflammation
2个月前
已完结