Lv11
32 积分 2025-12-02 加入
Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure–Activity Relationship Studies
1小时前
已完结
Design, synthesis, and evaluation of phenylglycinols and phenyl amines as agonists of GPR88
1小时前
已完结
Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation
2小时前
已完结
Discovery of a Novel Lung-Restricted ALK5 Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis
21天前
已完结
Discovery and Evaluation of Clinical Candidate AZD3759, a Potent, Oral Active, Central Nervous System-Penetrant, Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
21天前
已完结
Aminoisoquinolines: design and synthesis of an orally active benzamidine isostere for the inhibition of factor XA
22天前
已完结
Substituted acrylamides as factor Xa inhibitors: improving bioavailability by P1 modification
22天前
已完结
Structure-Based Design of New LSD1/EGFRL858R/T790M Dual Inhibitors for Treating EGFR Mutant NSCLC Cancers
22天前
已完结
Discovery of Novel Fourth-Generation EGFR Inhibitors to Overcome C797S-Mediated Resistance
22天前
已完结
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