Lv21
174 积分 2023-01-24 加入
Harnessing the E3 Ligase KLHL12 for Tumor‐Selective Protein Degradation
3小时前
待确认
Discovery of Highly Potent and Selective, Orally Bioavailable BTK-Targeting PROTACs Featuring Novel CRBN-Binding Warheads
11小时前
已完结
Selective and Potent First-in-Class CRBN-Dependent Molecular Glue Degraders of WW Domain-Binding Protein 4
1个月前
已完结
Pharmacological Targeting of IRF4 As a Therapeutic Strategy for Multiple Myeloma
2个月前
已完结
Piercing myeloma’s Achilles’ heel
2个月前
已完结
Piercing myeloma’s Achilles’ heel
3个月前
已完结
Glycoengineered Host-Guest Nanoparticles Potentiate Alzheimer’s Disease Therapy via Lesion-Specific Modulation of Tau Pathology
3个月前
已完结
Contemporary trends in targeted protein degradation for neurodegenerative diseases
3个月前
已完结
Discovery of a Potent, Selective and In Vivo Active Aurora A PROTAC Degrader from a Promiscuous Kinase Inhibitor
3个月前
已完结
Design, synthesis, and biological evaluation of novel PROTACs based on unnatural dipeptide CRBN ligands
5个月前
已完结