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40 积分 2026-01-15 加入
Dual tumor microenvironment-responsive albumin nanoplatform integrates conditional PROTAC activation with starvation and ferroptosis for synergistic cancer therapy
12小时前
求助中
A novel bispecific antibody targeting OX40L and TNFα for the targeted treatment of rheumatoid arthritis
12小时前
待确认
Carrier-Free Nano-Proteolysis Targeting Chimeras Enable Selective Protein Degradation and Enhance Photoimmunometabolic Therapy against Lung Adenocarcinoma
12小时前
已完结
An Acidosis-Activatable Nanocomposite for Synergistic Microenvironment Remodeling and Reprogramming of Innate–Adaptive Immune Crosstalk in Rheumatoid Arthritis
5天前
已完结
Molecular Engineering of Curcumin-Based Lysosome-Targeting Photosensitizers for Boosting Tumor Photoimmunotherapy via Ferroptosis/Pyroptosis Activation and Autophagy Inhibition
5天前
已完结
A ROS-Responsive Dimeric Prodrug Nanoassembly for Amplified Epigenetic Therapy of Lymphoma
10天前
已完结
Discovery and Evaluation of E0714 as an Antiepileptic Candidate: A Highly Subtype-Selective Kv7 Agonist within the Kv7 Family Designed Based on a Kv7.2-Specific Pocket
14天前
已完结
PROTAC-Mediated Degradation of mHTT Aggregates Attenuates Neurotoxicity in Cellular and R6/2 Mouse Models of Huntington’s Disease
14天前
已完结
Targeted GPX4 Degradation Mediated by Hypoxia-Overcoming Nano-PDTACs for Synergistic Ferroptosis-Immunotherapy
14天前
已完结
Sinomenine treats Rheumatoid Arthritis by regulating IL-6 Gene Promoter Methylation
24天前
已完结
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