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78 积分 2024-09-13 加入
Synthesis Optimization, Scale-Up, and Catalyst Screening Efforts toward the MGAT2 Clinical Candidate, BMS-963272
16小时前
待确认
Development of Scalable Synthesis of Chiral Sultam via a Chiral Phosphoric Acid-Promoted tert-Butyl Carbamate Deprotection–Resolution Sequence or Diastereoselective Hydrogenation
2个月前
已完结
A Second-Generation Route to the Cereblon Fragment of ARV-471, Vepdegestrant
2个月前
已完结
Development of a Commercial Manufacturing Process for Vepdegestrant, an Orally Bioavailable PROTAC Estrogen Receptor Degrader for the Treatment of Breast Cancer
2个月前
已完结
Comprehensive Synthetic Route Redesign of AZD5991: A High-Complexity Atropisomeric Macrocycle
7个月前
已完结
A Practical and Efficient Vilsmeier Synthesis of 3-Chloroindole-2-carboxaldehydes
7个月前
已完结
Fluorination‐Oxidation of 2‐Hydroxymethylindole Using Selectfluor
7个月前
已完结
Commercial Route Development of Sigma-2 Receptor Modulator, CT1812 Leveraging Photoflow, and HTS Technologies
7个月前
已完结
Development of a Scalable Synthesis of a HPK1 Inhibitor Featuring a Direct α-Arylation of Boc-Protected
7个月前
已完结