Lv11
48 积分 2025-05-24 加入
Design, Synthesis, and Pharmacodynamic Evaluation of Highly Selective PARP1 Inhibitors with Brain Penetrance
1小时前
待确认
Discovery and Pharmacological Evaluation of Potent and Highly Selective PARP1 Inhibitors
2小时前
已完结
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
2小时前
已完结
Discovery of the PARP (poly ADP-ribose polymerase) inhibitor 2-(1-(4,4-difluorocyclohexyl)piperidin-4-yl)-1H-benzo[d]imidazole-4-carboxamide for the treatment of cancer
22天前
已关闭
Design, synthesis and antitumor activities of phthalazinone derivatives as PARP-1 inhibitors and PARP-1/HDAC-1 inhibitors
22天前
已关闭
An allosteric mechanism for potent inhibition of SARS-CoV-2 main proteinase
1个月前
已完结
Poly-ADP-ribose polymerase (PARP) inhibitors and ovarian function
1个月前
已关闭
Clinical and translational advances in ovarian cancer therapy
1个月前
已完结
Artificial intelligence in drug development
1个月前
已完结
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
1个月前
已完结
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