Lv1
58 积分 2025-05-24 加入
Artificial intelligence in drug development
2个月前
已完结
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir
2个月前
已完结
Exploration of SARS-CoV-2 3CLpro Inhibitors by Virtual Screening Methods, FRET Detection, and CPE Assay
5个月前
已完结
Topotecan induces apoptosis via ASCT2 mediated oxidative stress in gastric cancer
5个月前
已完结
Preclinical Characterization of AZD9574, a Blood–Brain Barrier Penetrant Inhibitor of PARP1
7个月前
已完结
Design, Synthesis, and Pharmacodynamic Evaluation of Highly Selective PARP1 Inhibitors with Brain Penetrance
7个月前
已完结
Discovery and Pharmacological Evaluation of Potent and Highly Selective PARP1 Inhibitors
7个月前
已完结
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
7个月前
已完结
Discovery of the PARP (poly ADP-ribose polymerase) inhibitor 2-(1-(4,4-difluorocyclohexyl)piperidin-4-yl)-1H-benzo[d]imidazole-4-carboxamide for the treatment of cancer
7个月前
已关闭
Design, synthesis and antitumor activities of phthalazinone derivatives as PARP-1 inhibitors and PARP-1/HDAC-1 inhibitors
7个月前
已关闭