Lv11
38 积分 2025-05-24 加入
Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancer
3小时前
待确认
Carbamoylation at C-8 position of natural 3-arylcoumarin scaffold for the discovery of novel PARP-1 inhibitors with potent anticancer activity
19天前
已完结
Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors
2个月前
已完结
Design, synthesis and antitumor activities of phthalazinone derivatives as PARP-1 inhibitors and PARP-1/HDAC-1 inhibitors
2个月前
已完结
Design, synthesis and antitumor activities of phthalazinone derivatives as PARP-1 inhibitors and PARP-1/HDAC-1 inhibitors
2个月前
已完结
Structure-based design, synthesis, and evaluation of inhibitors with high selectivity for PARP-1 over PARP-2
3个月前
已完结
Artificial intelligence in drug development
8个月前
已完结
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir
8个月前
已完结
Exploration of SARS-CoV-2 3CLpro Inhibitors by Virtual Screening Methods, FRET Detection, and CPE Assay
10个月前
已完结
Topotecan induces apoptosis via ASCT2 mediated oxidative stress in gastric cancer
10个月前
已完结
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