Lv1
98 积分 2025-05-13 加入
DeepDegradome: A structure-aware deep learning framework for PROTAC and ligand generation against protein targets
1个月前
已完结
Targeting thymine DNA glycosylase induces synthetic lethality in p53-deficient cancers
1个月前
已完结
Steroidal hormones and neurosteroids - novel therapeutic strategies in bacterial infections: Design, synthesis, and biological evaluation
1个月前
已关闭
Structure-Guided Discovery of Subtype Selective SIRT6 Inhibitors with a β-Carboline Skeleton for the Treatment of Breast Cancer
1个月前
已完结
Identification of a Potent Oridonin Analogue for Treatment of Triple-Negative Breast Cancer
1个月前
已完结
Discovery of SIRT1-Activating Hydrogen Sulfide Donating Derivatives for Efficient Resistant of Myocardial Ischemic Injury
1个月前
已完结
Design and SAR of Withangulatin A Analogues that Act as Covalent TrxR Inhibitors through the Michael Addition Reaction Showing Potential in Cancer Treatment
1个月前
已完结
Small-molecule inhibition of YTHDC1 as a strategy against acute myeloid leukemia in mouse models
1个月前
已完结
A New Class of PotentN-Methyl-d-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications
1个月前
已完结
Design, Synthesis, and Investigation of Anti-liver Fibrosis Activity of Steroidal VDR Modulators via Side-Chain Modifications
1个月前
已完结