Lv7
3964 积分 2021-08-20 加入
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
12小时前
已完结
Integrating Multimodal AI with Encoded Medicinal Knowledge and Physics Simulations: A Unified Platform for Accelerated Drug Discovery from Patent Analysis to Potency Validation
25天前
已完结
Design, synthesis, and biological evaluation of ML162-based glutathione peroxidase 4 (GPX4) degraders with hydrophobic tags
2个月前
已完结
Large-Scale Collaborative Assessment of Binding Free Energy Calculations for Drug Discovery Using OpenFE
2个月前
已完结
Discovery of Non-benzoazacyclic V 2 R Antagonists for the Treatment of Autosomal Dominant Polycystic Kidney Disease
6个月前
已完结
Cryo-EM structure enabling virtual screening for the discovery of highly potent TRPM3 antagonists with analgesic efficacy
6个月前
已完结
Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC
6个月前
已完结
Discovery of novel co-degradation CK1α and CDK7/9 PROTACs with p53 activation for treating acute myeloid leukemia
6个月前
已完结
Discovery of a selective CDK7 PROTAC against acute leukemia with low platelet toxicity
6个月前
已完结
Discovery of a selective CDK7 PROTAC against acute leukemia with low platelet toxicity
7个月前
已完结