Lv75
4080 积分 2023-11-15 加入
Selective TYK2 inhibitors as potential therapeutic agents: a patent review (2019–2021)
18天前
已完结
Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Binds to Tyk2 JH2
18天前
已完结
Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core
1个月前
已完结
Insights on JAK2 Modulation by Potent, Selective, and Cell-Permeable Pseudokinase-Domain Ligands
1个月前
已完结
Progress on the Pharmacological Targeting of Janus Pseudokinases
1个月前
已完结
TO MARKET, TO MARKET—2023: SMALL MOLECULES
1个月前
已完结
Design, Synthesis, and Biological Evaluation of Macrocyclic 2-Amino-4-phenylaminopyrimidine Derivatives as Potent JAK2 Inhibitors
1个月前
已完结
Derisking Affinity Optimization for Macrocycles and Cyclic Peptides: High-Precision Free Energy Simulations across Five Diverse Targets
1个月前
已完结
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain
2个月前
已完结
Solute carrier family 15 member 4, an emerging therapeutic target for systemic lupus erythematosus
2个月前
已完结
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