Lv2
138 积分 2025-07-27 加入
Discovery of Oral Degraders of the ROS1 Fusion Protein with Potent Activity against Secondary Resistance Mutations
8天前
已完结
A Buchwald–Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3‐Ligase PROTACs**
13天前
已完结
The synthetic landscape of cereblon (CRBN) binders: from thalidomide to emerging chemotypes
1个月前
已完结
A dihydrouracil CRBN ligand mitigates IMiD associated safety liabilities in heterobifunctional targeted protein degrader
1个月前
已完结
Molecular Glues Recruiting RNF213 As an E3 Ligase for Targeted Protein Degradation: A Minimal Dibromoacetamide Warhead As a Recruitment Ligand
3个月前
已完结
Discovery of SD-2301 as a Highly Potent and Selective PROTAC STAT3 Degrader Capable of Achieving Complete Tumor Regression with Single Administration
3个月前
已完结
A Facile Method for Nucleophilic Aromatic Substitution of Cyclic Amine
4个月前
已完结
Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19
5个月前
已完结
Identification of a Selective YTHDF1 Inhibitor Targeting the m6A Recognition Domain for Breast Cancer
6个月前
已完结
The Witkop-Winterfeldt-Oxidation of Indoles
9个月前
已完结
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