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50 积分 2026-04-27 加入
Discovery of stereoselective targeted covalent inhibitors of the RAB27-effector protein-protein interaction
17天前
已关闭
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
23天前
已完结
In Situ Formed N-Sulfonyl Guanidinium for Efficient Amide Coupling
25天前
已完结
Structural Modification and Prodrug Design Based on Natural Stilbene Scaffold for the Discovery of Novel PARP-1 Inhibitors with Improved Antitumor Activity
1个月前
已完结
Targeted Degradation of Capsid by Host-Hijacking PROTAC Overcomes Drug Resistance
1个月前
已完结
RIMTAC: A Novel Degrader Design Platform by Indirect VHL-Recruitment via RIPK1
1个月前
已完结
Covalent Protein Inhibitors via Tyrosine and Tryptophan Conjugation with Cyclic Imine Mannich Electrophiles
3个月前
已完结
Allosteric inhibition of the PCSK9–LDLR interaction: structural insights for small molecule design
3个月前
已完结
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