Lv1
46 积分 2025-10-13 加入
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
21天前
已完结
Targeting STING with covalent small-molecule inhibitors
1个月前
已完结
Development and potential clinical uses of human prolactin receptor antagonists
1个月前
已完结
New mechanisms for PRLr action in breast cancer
1个月前
已完结
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
2个月前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
2个月前
已完结
Discovery of Potent, Selective, and In Vivo Efficacious AKT Kinase Protein Degraders via Structure–Activity Relationship Studies
3个月前
已完结
Inhibition of Cyclic GMP ‐ AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1 ‐Deficient Mice
4个月前
已完结
Development of dual AR/ARV7 degraders with 3,5-dimethylisoxazole to overcome antiandrogen resistance in castration-resistant prostate cancer
4个月前
已完结