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98 积分 2023-06-02 加入
Synthetic lethality: targeting the SMARCA2 bromodomain for degradation in SMARCA4-deficient tumors – a review of patent literature from 2019–June 2023
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Recent Advances in Glutarimide Chemistry for Cereblon-Mediated Targeted Protein Degradation: Developments in Synthesis and Diversification
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Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs
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Development of a Buchwald–Hartwig Amination for an Accelerated Library Synthesis of Cereblon Binders
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PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4 -Mutated Cancers
2个月前
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Exquisite Sensitivity to Dual BRG1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid Leukemia
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