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31 积分 2020-09-14 加入
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
2天前
已完结
An updated literature on BRAF inhibitors (2018–2023)
7天前
已完结
Degrons: defining the rules of protein degradation
13天前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
16天前
已完结
Discovery of Pyrazolo[1,5,4-de]quinoxalin-2(3H)-one Derivatives as Highly Potent and Selective PARP1 Inhibitors
1个月前
已完结
Optimization of α-Fluoro, β-Heteroaryl Acrylamide Warheads for KRAS G12C Active-State Inhibition
1个月前
已完结
Optimization of Covalent Warhead Trajectory for KRAS G12C Active-State Inhibition
1个月前
已完结
Some Recent Observations on the Role of Carbon Tetrel Bonding in Drug Design
1个月前
已完结
Application of Bioisosteres in the Design and Discovery of FDA-Approved Drugs and Advanced Clinical Candidates
2个月前
已完结
Identification and Optimization of Pyridone Derivatives as Pan-MEK/RAF Nondegrading Molecular Glues for the Treatment of RAS-Driven Cancers
2个月前
已完结
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