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10 积分 2021-07-06 加入
Discovery of Covalent and Cell‐Active ALKBH5 Inhibitors with Potent Antileukemia Effects In Vivo
1天前
已完结
Discovery of a Covalent HDAC3 Degrader with Excellent Anti-Inflammatory Activity and NLRP3 Inflammasome Suppression
2天前
已完结
Unleashing the Power of Covalent Drugs for Protein Degradation
2天前
已完结
Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes
2天前
已完结
A Tandem Bioorthogonal Retro-Cope and Cope Elimination for the Activation of Covalent Inhibitors with an Acrylamide or Vinylsulfonamide Warhead in Live Cells
2天前
已完结
Targeting Non-BET Bromodomains: Emerging Opportunities in Drug Discovery
2天前
已完结
In-Cell Approach to Evaluate E3 Ligases for Use in Targeted Protein Degradation
2天前
已完结
Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs
3天前
已完结
Biomimetic cartilage-lubricating polymers regenerate cartilage in rats with early osteoarthritis
6天前
已完结
Discovery, Synthesis, and Evaluation of Novel Dual Inhibitors of a Vascular Endothelial Growth Factor Receptor and Poly(ADP-Ribose) Polymerase for BRCA Wild-Type Breast Cancer Therapy
17天前
已完结
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