Lv11
40 积分 2021-07-06 加入
Discovery of Dual PD-L1/HDAC3 Inhibitors for Tumor Immunotherapy
2小时前
已完结
Degradation of Hexokinase 2 Blocks Glycolysis and Induces GSDME-Dependent Pyroptosis to Amplify Immunogenic Cell Death for Breast Cancer Therapy
8天前
已完结
Discovery and Proof of Concept of Potent Dual Polθ/PARP Inhibitors for Efficient Treatment of Homologous Recombination-Deficient Tumors
2个月前
已完结
Discovery of a Novel Covalent EZH2 Inhibitor Based on Tazemetostat Scaffold for the Treatment of Ovarian Cancer
2个月前
已完结
Discovery of Covalent and Cell‐Active ALKBH5 Inhibitors with Potent Antileukemia Effects In Vivo
2个月前
已完结
Discovery of a Covalent HDAC3 Degrader with Excellent Anti-Inflammatory Activity and NLRP3 Inflammasome Suppression
2个月前
已完结
Unleashing the Power of Covalent Drugs for Protein Degradation
2个月前
已完结
Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes
2个月前
已完结
A Tandem Bioorthogonal Retro-Cope and Cope Elimination for the Activation of Covalent Inhibitors with an Acrylamide or Vinylsulfonamide Warhead in Live Cells
2个月前
已完结
Targeting Non-BET Bromodomains: Emerging Opportunities in Drug Discovery
2个月前
已完结
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